BizTalk's end-of-life is the start of business breakthroughs with Axway B2B
With Microsoft BizTalk end-of-life looming, customers are moving to Axway for secure, reliable B2B/EDI, API, and iPaaS integration with flexibility to deploy on Azure and other platforms.
Axway B2B processes 1 billion messages annually and $140 billion in revenue. Here’s what else Axway enables:
3 of 4
major credit card companies
40%
of U.S. GDP
Top 10
automotive manufacturers
Comparing Axway B2B and Microsoft BizTalk
How do Axway B2B Integration and Microsoft BizTalk measure up in supporting the needs of large national or multinational enterprises?
| Axway B2B Integration | Microsoft BizTalk1 | |
|---|---|---|
| Ready for any use case complexity |
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| Flexible deployment options |
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| Reliable 24/7 customer support |
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| Future-ready strategy and vision |
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| User self-service and automation |
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| Added-value ecosystem beyond EDI |
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| Transparent, predictable pricing |
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1Axway perspective based on subjective evaluation | ||
Axway B2B Integration
Microsoft BizTalk1
Ready for any use case complexity
Flexible deployment options
Reliable 24/7 customer support
Future-ready strategy and vision
User self-service and automation
Added-value ecosystem beyond EDI
Transparent, predictable pricing
1Axway perspective based on subjective evaluation
"For integration we do have two technologies EDI and API, and our partner Axway is one of the key enablers to help us on this integration. We operate them in 160 countries where we are distributing so all around the world."
Bérangère Tomsin
Why to switch from MS BizTalk to Axway B2B
Many companies are confidently modernizing with Axway B2B, a future-ready solution offering greater flexibility, better support, simplified operations, and scalable partner integration.
Our innovation moves with your business
We continuously update B2Bi based on customer feedback, security, and trends like multi-clustering and containerization. We are an API-first vendor that supports all the complexity of B2B/EDI flows through managed, SaaS, hybrid, and customer-managed models.
We simplify B2B integration – not complicate it
Our unified B2B platform blends API, EDI, AI and iPaaS-driven integration. No more siloed tools – just faster partner connections and support for networks like e-invoicing, VANs, and more.
Our support comes with enterprise-grade security
Our customers trust us to protect sensitive transactions and ensure business continuity without relying on fragmented or third-party tools. Our in-house experts offer 24/7 support, smooth migration, and tailored professional services.
We let you integrate without IT tickets
Axway is built for business integration users, not just IT. With intuitive self-service tools for onboarding, tracking, and management, you can handle it all – quickly, easily, and without calling your IT team.
Leader Fall 2025
Best Support Enterprise Fall 2025
Leader Enterprise Fall 2025
Regional Leader APAC Fall 2025
Axway B2B Integration
Respond faster to B2B integration business demands with a modern solution that provides access to a great variety of EDI protocols, APIs, modern VAN, WebEDI Supplier Portal, and other means of communication.
Axway B2B capabilities outperform MS BizTalk
With out-of-the-box API automation, unifying EDI and API flows and more, Axway B2B goes beyond BizTalk’s limitations. For going the extra mile with custom connectors and iPaaS-like capabilities, Amplify Fusion is here to support you.
Axway B2Bi
Partner network management and support for EDI and API standards securely in the cloud or on-premises
Axway B2Bi Enterprise Edition
Streamline and secure your B2B through containerization while preserving active/active and multi-clustering
Axway B2B Cloud Services
Delegate all or some of your B2B operations to Axway experts
Axway VAN
Single point of management for handling of EDI and internet-based protocols with the capability of a modern, API-driven value-added network (VAN).
Axway eInvoicing
Global approach to managing e-invoicing, eliminating the headaches of managing buyer or supplier-based processes and dealing with multiple vendor portals.
Axway Peppol Access Point
Manage the transition from paper to digital invoicing safely and effortlessly.
Questions to ask about MS BizTalk
If you’re wondering whether or not you should stick with BizTalk, here are some questions you deserve answers to:
Do you need to onboard new trading partners quickly and at scale?
Is partner onboarding slow or IT-dependent? Axway offers self-service portals that empower business users to onboard partners faster without heavy IT involvement.
Are you ready to support complex EDI use cases quickly without custom work or manual interventions?
If the business needs it tomorrow, could you roll out a new EDI flow using multiple protocols or standards (like AS2, SFTP, EDIFACT, etc.) right out of the box? Do you have the flexibility to adapt to different partner requirements without building custom logic each time? Is your current solution scalable or are you relying on workarounds to meet evolving needs?
Are you looking for a vendor that can support both traditional B2B/EDI integration and modern API-driven, connector-based iPaaS workflows?
How critical is it for your organization to maintain robust B2B protocol support alongside API management? Do you require seamless orchestration between traditional EDI flows and modern iPaaS-based services? This is exactly where Axway excels.
Are you managing compliance-heavy or regulated B2B data exchanges (e.g., e-invoicing, automotive, healthcare, financial)?
Do your integrations require strict compliance and audit trails? Axway’s platform is built to meet regulatory demands, reducing risk and simplifying audits.
Are you using a VAN or direct connections to manage EDI traffic?
Do you manage multiple VANs or direct partner links? Axway provides both, direct EDI and a modern API-driven VAN to simplify partner communication, reducing complexity and cost.
Let's Talk
Migrations can be difficult, especially when your business depends on the exchange of data to keep running. Don’t worry, we have a wealth of in-house expertise and proven processes that have enabled us to help companies like yours move to Axway countless times before.
Let's Talk
Migrations can be difficult, especially when your business depends on the exchange of data to keep running. Don’t worry, we have a wealth of in-house expertise and proven processes that have enabled us to help companies like yours move to Axway countless times before.